Grants supported under the National Research Excellence Program 

2024:

• NKKP_ADVANCED_24 - ADVANCED: Andrea Bodor – Atomic-level characterization of molecular crowding and phase separation of single-stranded DNA-binding (SSB) proteins
• NKKP_ADVANCED_24 - ADVANCED: Ádám Miklósi – Outsourced control: Positive feedback loops between digital self-regulation, mobile addiction, and ADHD in children and adolescents
• NKKP_ADVANCED_24 - ADVANCED: Mihály Kovács – Biochemical, genetic, and pharmacological targeting of stress response based on nucleoprotein condensation
• NKKP_ADVANCED_24 - ADVANCED: Imre Salma – Effects of aerosols on urban air quality and climate
• NKKP_ADVANCED_24 - ADVANCED: Tamás Székely – The impact of global environmental changes on the evolution of reproductive systems
• NKKP_EXCELLENCE_24 - EXCELLENCE: Dömötör Pálvölgyi – Combinatorics and Geometry

List of projects funded by the National Excellence Program (2018-1.2.1-nkp)

• András Perczel: Protein science and its applications national program
• Péter Sziklai: The mathematical foundation of artificial intelligence

High-value research and infrastructure tenders funded in the framework of the Competetive Central Hungary Operative Program (vekop)

• András Perczel: Designation and development of biocompatible nano and mezo systems based on amyloid spinning
• Anna Erdei: Establishment of a spinning disc, tirf and confocal laser microscope center to rapid display of molecular processes and interactions in living cells
• Ferenc Fodor: High resolution roentgen fluorescent element analytical dispersion investigation in floral, animal and inorganic objects
• István Groma: Nanocharacterization laboratory for the development of modern materials
• András Perczel: Development of NMR spectroscopy infrastructure for the biocompatible nano-rational composition and production of peptide mimetics and peptide medicines
• Veronika Harmat: Development of ELTE’s X-ray crystallography infrastructure for the analysis of the structure and interactions of biomacromolecules and biologically active molecules
• Ádám Miklósi: High-tech laboratory complex for the comparative analysis of neurobiological, physiological and behavioral changes
• Ferenc Hudecz: Development of modern infrastructure for the analysis of new synthetic and natural origin anti-tumor and antimicrobal agents and delivery assisting conjugates
• Imre Kacskovics: Application of flow citofluorimeters for the development and analysis of diagnostical and research antidotes

High-value research tenders funded in the framework of the economic development and innovation operative program (ginop)

• Zoltán Barcza: Establishment of an interdisciplinar research workshop for a climate-adaptive and sustainable agriculture
• Károly Márialigeti: Establishment of a soil biome transdisciplinar excellence center for securing sustainable soil resources

High-value research tenders funded in the framework of the national competetiveness and excellence program (nvkp)

• Ildikó Világi: Study of effects influencing the level of fusarium infection in cereals, the analysis of the medical and sensory effects of infected food and forage and the investigation of the possibilities of risk reduction
• Gábor Mező: Development of bioconjugates and their modules capable of targeted treating of high mortality rate tumorous diseases
• Gyula Záray: Development of an innovative photooxidation water purification technology to remove organic microcontamination from biologically purified waste water
• András Málnási-Csizmadia: Development of Neurelaxin, the first agent stimulating neuron projection development: the lead compound assisting the restoration of stroke and other brain disorders

Large-scale bilateral research and technology cooperations

• Nguyen Quang Chinh: Study of grain phenomenon and development of low-temperature super-malleable malleability in ultra-fine grain high-strength aluminium alloys
• Jenő Gubicza: Mechanical and electrochemical attributes of hierarchical structure nano-pore tyrolites

2023-1.1.1-PIACI_FÓKUSZ projects at the Faculty

• Máté Csanád, Imre Kacskovics: Development of a modular detector and illumination system for studying light scattering of shaped elements across all angular ranges, primarily for hematological applications. (Joint research with NORMA Instruments Zrt.)

Investment in the Future

• Development of Targeted Therapy for Human Tumors Expressing Mutant K-Ras Oncogene

  The consortium, led by the Research Centre for Natural Sciences, aims to identify effective inhibitors for mutant KRas proteins. This effort is based on a combination of already known and newly determined 3D structural information, utilizing the most advanced fragment-based molecular design methods. The project, funded with HUF 350 million, involves the Faculty of Science at ELTE, Semmelweis University, and KINETO Lab Ltd.

  Scientific Contact: András Perczel
  E-mail: perczel.andras@ttk.elte.hu
  Go to the project subpage

• Development and Validation of New COVID-19 Specific Laboratory Assays for Mass Testing (Detection of Coronavirus-Specific RNA and Antibodies) in an Institutional Pilot Study

  With HUF 350 million in funding from the NKFI Fund, this project is carried out through the collaboration of the Faculty of Science at ELTE, the South Pest Central Hospital – National Institute of Hematology and Infectious Diseases, the University of Pécs, and ImmunoGenes-ABS Ltd.

  The consortium leader, ELTE TTK Biological Institute, is developing new, cost-effective, high-throughput diagnostic methods to support the fight against COVID-19. The production of the necessary recombinant protein enzymes builds on the institute’s outstanding professional competencies and state-of-the-art laboratory infrastructure established in recent years.

  Scientific Contact: Imre Kacskovics
  E-mail: imre.kacskovics@ttk.elte.hu
  Go to the project subpage

• Investigation and Application of Factors Providing Natural Immunity Against Coronavirus Infection in Plasma Therapy

  This project, led by the National Blood Supply Service, focuses on the study and application of naturally occurring protective factors against coronavirus infection in plasma therapy. The research is conducted in collaboration with Semmelweis University, ELTE, and the University of Physical Education, supported by HUF 400 million from the NKFIH Fund, running from January 1, 2021, to December 31, 2023.

  Scientific Contact: Mihály Józsi
  E-mail: mihaly.jozsi@ttk.elte.hu
  Go to the project subpage

GINOP PLUS – Encouraging Corporate Research, Development, and Innovation Activities

• Development of Intelligent Hybrid Cutting Tools and an Integrated Quality Assurance Marking System for Automotive Leather Cutting Systems

The project, led by Pangea Made Ltd., runs from February 1, 2022, to January 31, 2025. Researchers from the ELTE TTK Department of Operations Research are developing die-cutting blades using 3D metal printing with a funding of HUF 139,901,780. These blades combine durability with the freedom of shape selection, enabling fast and efficient production while also integrating solutions for the unique marking of cut leather pieces.

Scientific Contact: Alpár Jüttner
E-mail: alpar.juttner@ttk.elte.hu
Go to the project subpage

 Support for Market-Driven Research, Development, and Innovation Projects

• Development of Digital Microscopy for Oncopathological, Personalized Precision Diagnostics

With funding from the NKFI Fund, 3DHISTECH Ltd., ELTE, and Semmelweis University are developing a digital microscope and an oncopathological case management system as part of this project. The total project budget amounts to HUF 1.176 billion, with consortium members securing HUF 693.5 million in funding.

Researchers at the ELTE Faculty of Science are utilizing HUF 80 million to develop an AI-based algorithm and procedure for classifying tumor diagnostic and therapeutic targets.

Scientific Contact: István Csabai
E-mail: istvan.csabai@ttk.elte.hu
Go to the project subpage

SME Focus Area Innovation Program

• Classification of Radioactive Waste Using a Mobile Container-Based Measurement Station and Detector Network Technology

The new project, launching in February 2025, is a collaboration between GAMMA Zrt. and Eötvös Loránd University (ELTE) to enhance the efficient management of radioactive waste, thereby reducing its environmental impact.

The project's goal is to develop a state-of-the-art system of instruments and procedures that offers a cost-effective, fast, and reliable solution for classifying radioactive waste packages. This advancement will revolutionize the methods required for the so-called waste clearance procedure, essential in radioactive waste management.

Researchers from the Faculty of Science at ELTE, including physicists and chemists, contribute to various aspects of the project, primarily through supportive simulations, experimental research, and measurements. The university’s participation is coordinated by Ákos Horváth and Gábor Veres from the Department of Atomic Physics, along with Zoltán Homonnay from the Department of Analytical Chemistry.

Scientific Contact: Gábor Veres
E-mail: vg@ludens.elte.hu

(Translated by AI)