Protein stability, folding, misfolding. Structural and thermodynamic background of protein aggregation and amyloid formation. Intermolecular interactions. The role of the complement system in the brain. Method development to estimate the secondary structure and fold of proteins from the CD spectrum. Experienced in biophysical and spectroscopy techniques, such as circular dichroism (CD) and infrared spectroscopy and isothermail titration calorimetry, enzyme kinetics, protein expression and purifucation, gene technology.