Dr. Imre Derényi
Dr. Imre Derényi
Professor
Corresponding Member of the Hungarian Academy of Sciences
Contact details
Address
1117 Budapest, Pázmány Péter sétány 1/a.
Room
3.78
Phone/Extension
6366
Links
  • 1. Natural sciences
    • 1.3 Physical sciences
    • 1.6 Biological sciences
      • Biophysics
      • Theoretical biology
Somatic evolution

My research focuses on a deeper understanding of somatic evolution in multicellular organisms. During their development and life, multicellular organisms constantly produce new cells. Each cell division involves the duplication of the genetic material, which is a fairly precise but not completely error-free process, and results in the appearance of genetic mutations. The accumulation of mutations is very harmful because it leads to the deterioration of the functioning of cells and organs (or even to the development of cancer). Using theoretical (population dynamics) models I investigate what type of cell divisional and tissue structural strategies can ensure tissue renewal while minimizing the rate of mutation accumulation. Analyzing whole-genome sequence data from various parts of the same plant, I aim to uncover the organization and dynamics of stem cells during the growth and bud formation of vascular plants.